IT

Female sexual dysfunctions: future of medical therapy

28/02/2011

Female sexual dysfunctions: future of medical therapy
in: Abdel-Hamid I.A. (Ed), Advances in sexual medicine: drug discovery issues, Research Signpost, Kerala, India, 2009, p. 403-432
Female sexual dysfunction (FSD) is age related, progressive and highly prevalent, affecting up to 20% to 43% of women in the fertile age, and 48% of the older postmenopausal women. Pelvic floor disorders are among the most important and yet neglected medical contributors to womens' sexual dysfunctions.
This chapter will briefly review the pathophysiology of women's sexual function and dysfunction, and focus on clinical use of hormonal (hormone therapy (HT), tibolone, testosterone patches) and non-hormonal agents including those impacting the central nervous system (CNS), such as bupropion, flibanserin, and bremelanotide, in the treatment of FSD. New perspectives on genital treatments: hormonal (vaginal estrogens, vulvar testosterone) and non hormonal (vasoactive drugs, botulin toxin) will be briefly considered.

Available documents:Full text of the chapter

Keywords:
Addictions Ageing Arousal Arousal Disorders Biological Factors Botulin Toxin Central Nervous System Comorbidity Couple Factors Depression Desire Disorders Differential diagnosis Dopamine Drugs Ecosystems Epidemiology Estrogens Female Dyspareunia / Pain after intercourse Female Genital System Female Sexual Disorders Female Sexual Function Gynaecology Hormone Replacement Therapy (HRT) Hyperactive Pelvic Floor Hyperactive Pelvic Floor Hypoactive Pelvic Floor Hypoactive sexual desire disorder (HSDD) Intimacy Lifestyles Local Hormonal Therapy Male Sexual Disorders Menopause / Perimenopause Neuroplasticity Neurotransmitters Orgasm Orgasmic Disorders Pain Pain System Pelvic Floor Personal Distress Pharmacological therapy Premature Iatrogenic Menopause Progesterone / Progestins Psychoplasticity Psychosexual Factors Relational Factors Serotonin Sexual Desire Sexual Distress Sexual Hormones Sexual Identity Sexual Medicine Sexual Pain Disorders Sexual Relationship Testosterone Tibolone Uro-Gynaecology Vagina Vaginal Lubrication Vaginal pH Vaginismus Vulvar Vestibulitis / Provoked Vestibulodynia / Vulvodynia